Hydrogen Database (Updated 2026)
There are thousands of studies conducted on the benefits of molecular hydrogen.
We brought forth the most relevant to you.
The effects of 6-month hydrogen-rich water intake on molecular and phenotypic biomarkers of aging in older adults aged 70 years and over: A randomized controlled pilot trial – Experimental Gerontology – Link
Feasibility and Safety of Hydrogen Gas Inhalation for Post-Cardiac Arrest Syndrome—First-in-Human Pilot Study – Circulation Journal – Link
Hydrogen gas inhalation alleviates oxidative stress in patients with post-cardiac arrest syndrome – Journal of Clinical Biochemistry and Nutrition – Link
The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodeling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction—First Pilot Study in Humans – Circulation Journal – Link
Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function – Vascular Health and Risk Management – Link
Efficacy of inhaled hydrogen on neurological outcome following brain ischaemia during post-cardiac arrest care (HYBRID II): A multi-centre, randomised, double-blind, placebo-controlled trial – EClinicalMedicine – Link
Intravenous Hydrogen Therapy With Intracisternal Magnesium Sulfate Infusion in Severe Aneurysmal Subarachnoid Hemorrhage – Stroke – Link
Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection – Journal of Stroke & Cerebrovascular Diseases – Link
Improved brain MRI indices in the acute brain stem infarct sites treated with hydroxyl radical scavengers, Edaravone and hydrogen, as compared to Edaravone alone. A non-controlled study – Medical Gas Research – Link
Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment – Current Alzheimer Research – Link
Therapeutic Inhalation of Hydrogen Gas for Alzheimer’s Disease Patients and Subsequent Long-Term Follow-Up as a Disease-Modifying Treatment: An Open Label Pilot Study – Pharmaceuticals – Link
Randomized, double-blind, multicenter trial of hydrogen water for Parkinson’s disease – Movement Disorders – Link
Effects of concomitant use of hydrogen water and photobiomodulation on Parkinson disease: A pilot study – Medicine – Link
Pilot study of H<sub>2</sub> therapy in Parkinson’s disease: A randomized double-blind placebo-controlled trial – Movement Disorders – Link
Hydrogen gas (XEN) inhalation ameliorates airway inflammation in asthma and COPD patients – QJM: An International Journal of Medicine – Link
Hydrogen/oxygen therapy for the treatment of an acute exacerbation of chronic obstructive pulmonary disease: Results of a multicenter, randomized, double-blind, parallel-group controlled trial – Respiratory Research – Link
Breathing Hydrogen-Oxygen Mixture Decreases Inspiratory Effort in Patients with Tracheal Stenosis – Respiration – Link
Hydrogen/oxygen mixed gas inhalation improves disease severity and dyspnea in patients with Coronavirus disease 2019 in a recent multicenter, open-label clinical trial – Journal of Thoracic Disease – Link
Molecular Hydrogen Positively Affects Physical and Respiratory Function in Acute Post-COVID-19 Patients: A New Perspective in Rehabilitation – International Journal of Environmental Research and Public Health – Link
Hydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with COVID-19: A retrospective study of medical records – Medicine – Link
A Gallbladder Carcinoma Patient With Pseudo-Progressive Remission After Hydrogen Inhalation – OncoTargets and Therapy – Link
Hydrogen gas therapy induced shrinkage of metastatic gallbladder cancer: A case report – World Journal of Clinical Cases – Link
Brain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report – OncoTargets and Therapy – Link
Hydrogen therapy can be used to control tumor progression and alleviate the adverse events of medications in patients with advanced non-small cell lung cancer – Medical Gas Research – Link
Hydrogen gas activates coenzyme Q10 to restore exhausted CD8+ T cells, especially PD-1+Tim3+ terminal CD8+ T cells, leading to better nivolumab outcomes in patients with lung cancer – Oncology Letters – Link
Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors – Medical Gas Research – Link
Hydrogen–oxygen therapy can alleviate radiotherapy-induced hearing loss in patients with nasopharyngeal cancer – Annals of Palliative Medicine – Link
Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer to improve prognosis – Oncology Reports – Link
Immunological Effect of Hydrogen Gas – Hydrogen Gas Improves Clinical Outcomes of Cancer Patients – Gan To Kagaku Ryoho (in Japanese) – Link
Two weeks of hydrogen inhalation can significantly reverse adaptive and innate immune system senescence in patients with advanced non-small cell lung cancer: A self-controlled study – Medical Gas Research – Link
Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes – Medical Gas Research – Link
Effects of hydrogen rich water on prolonged intermittent exercise – Journal of Sports Medicine and Physical Fitness – Link
Short-term H<sub>2</sub> inhalation improves running performance and torso strength in healthy adults – Biology of Sport – Link
Hydrogen-rich water suppresses the reduction in blood total antioxidant capacity induced by 3 consecutive days of severe exercise in physically active males – Medical Gas Research – Link
Drinking hydrogen water enhances endurance and relieves psychometric fatigue: A randomized, double-blind, placebo-controlled study – Canadian Journal of Physiology and Pharmacology – Link
Effectiveness of Oral and Topical Hydrogen for Sports-Related Soft Tissue Injuries – Postgraduate Medicine – Link
Molecular hydrogen affects body composition, metabolic profiles, and mitochondrial function in middle-aged overweight women – Irish Journal of Medical Science – Link
Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance – Nutrition Research – Link
Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome – an open label pilot study – Journal of Clinical Biochemistry and Nutrition – Link
Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome – Journal of Lipid Research – Link
The effects of 24-week, high-concentration hydrogen-rich water on body composition, blood lipid profiles and inflammation biomarkers in men and women with metabolic syndrome: A randomized controlled trial – Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy – Link
The Effects of Hydrogen-Rich Water on Blood Lipid Profiles in Clinical Populations: A Systematic Review and Meta-Analysis – Pharmaceuticals – Link
Consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: An open-label pilot study – Medical Gas Research – Link
Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: A randomized, double-blind, placebo-controlled pilot study – International Immunopharmacology – Link
Hydrogen in Patients With Corticosteroid-Refractory/Dependent Chronic Graft-Versus-Host-Disease: A Single-Arm, Multicenter, Open-Label, Phase 2 Trial – Frontiers in Immunology – Link
Hydrogen (H<sub>2</sub>) treatment for acute erythematous skin diseases. A report of 4 patients with safety data and a non-controlled feasibility study with H<sub>2</sub> concentration measurement on two volunteers – Medical Gas Research – Link
Effect of Supplementation With Hydrogen-rich Water in Patients With Interstitial Cystitis/Painful Bladder Syndrome – Urology – Link
Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies – Medical Gas Research – Link
Effect of Hydrogen-Rich Water on Oxidative Stress, Liver Function, and Viral Load in Patients with Chronic Hepatitis B – Clinical and Translational Science – Link
Hydrogen-rich water reduces liver fat accumulation and improves liver enzyme profiles in patients with non-alcoholic fatty liver disease: A randomized controlled pilot trial – Clinical Research in Hepatology and Gastroenterology – Link
Biological Effects of Hydrogen Water on Subjects with NAFLD: A Randomized, Placebo-Controlled Trial – Antioxidants – Link
A randomized, placebo-controlled clinical trial of hydrogen/oxygen inhalation for non-alcoholic fatty liver disease – Journal of Cellular and Molecular Medicine – Link
Effects of hydrogen in prevention of corneal endothelial damage during phacoemulsification: A prospective randomized clinical trial – American Journal of Ophthalmology – Link
A novel bioactive haemodialysis system using dissolved dihydrogen (H<sub>2</sub>) produced by water electrolysis: A clinical trial – Nephrology Dialysis Transplantation – Link
Novel haemodialysis (HD) treatment employing molecular hydrogen (H<sub>2</sub>)-enriched dialysis solution improves prognosis of chronic dialysis patients: A prospective observational study – Scientific Reports – Link